ADENOVIRUSES USING THE CANCER MARKER EPHA2 AS A RECEPTOR IN VITRO AND IN VIVO BY GENETIC LIGAND INSERTION INTO DIFFERENT CAPSID SCAFFOLDS.

Adenoviruses using the cancer marker EphA2 as a receptor in vitro and in vivo by genetic ligand insertion into different capsid scaffolds.

Adenoviral gene therapy and oncolysis would critically benefit from targeted cell entry by genetically modified capsids.This requires both the ablation of native adenovirus tropism and apac1/60/1/cw the identification of ligands that remain functional in virus context.Here, we establish cell type-specific entry of HAdV-5-based vectors by genetic li

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Traditional vs Online Games: Their Benefits for Young Learners

Abstract As young learners like to learn in a fun atmosphere with engaging interactions, the present study argues that when children learn English as a foreign language, implementing games in teaching English can benefit young learners.The research was conducted following the library research method, where the content of the research from previous

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Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation

During cell locomotion and endocytosis, membrane-tethered WASP proteins stimulate actin filament nucleation by the Arp2/3 complex.This process generates highly branched arrays of filaments that grow toward the membrane to which they are rumchata proof tethered, a conflict that seemingly would restrict filament growth.Using three-color single-molecu

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